DUALXtract Membrane Protein Optimization Kit

Extraction of Integral Membrane Proteins

Overcome common hurdles

Purification of membrane proteins is a complex, time consuming process and requires complete extraction and solubilization of the proteins from the membranes of the host cell. Common issues that are encountered are inefficient extraction of the protein of interest and inactivation of protein function and/or unfolding during extraction

The DUALXtract solutions provide optimal yet gentle conditions for efficient extraction and stabilization of membrane proteins from the cell membranes by using a variety of non-denaturing detergent and synthetic lipid analogs.

How it works

Step 1

Use the DUALXtract buffer set to test 12 different extraction buffers on your membrane protein of interest

Step 2

Once you have identified the optimal extraction buffer, use this buffer to perform a large scale extraction

Step 3

Continue with downstream work using the extracted membrane protein