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Nanoparticles for Difficult RNA Transfections

Dear Reader,

 

Hello from Bulldog Bio! You're a first time receiver of our newsletter - The Barker. We understand the value of your time, and so we only wish to present unique opportunities for improving the quality of your research experience. If you prefer not to receive The Barker, please unsubscribe at the bottom of this email. Thanks for taking time to read more about a new technology for better delivery of RNA molecules into cells.

 

Sincerely,

 

Bulldog Bio

Best in Show - PURPLE NIMT® Transfection Reagent

 

PURPLE is the first nanoparticle-based transfection reagent for siRNA.  Consisting of tiny iron spheres coated with carrier molecules - the result is a delivery system that is very gentle on cells.  In addition to seeing extremely low toxicity, you'll be able to quickly detect full knock-down effects in as little as 8 hours and lasting for days.  And did we mention that for difficult cell lines, the efficiency tends to be much greater than seen with lipid-only based reagents?  Click here to request a sample.

 

Advantages

  • Low toxicity to cells
  • Compatible with a wide range of cells
  • High transfection efficiency rate
  • Knockdowns in a fraction of the time
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    It's a Dog's Life-

    "real lab experience with our products"

     

    Low levels of cytotoxicity coupled with efficient uptake of RNA allows PURPLE Transfection Reagent to work with a wide variety of cells including: 786-O, EOC.20, ES, HEK293, hMSC, Jurkat, K562, MCF7, MEF, MiaPaCa, Panc-1, THP-1, U-87 and  U-2 OS cell lines.  Read some of our recent Application Notes on how PURPLE efficiently transfects human embryonic kidney and human renal cell carcinoma cell lines.

     

     

    Win a free bobble head in K9 Logic below!

     

    Throw Me a Bone

    If you are ordering any of our Transfection Tools products for the first time, we will include a case of 1000 Aloetouch ICE Nitrile Lab Gloves for free (a $95 value).  Just reference the following promotional code in your order: BTB002.  Your hands will thank you!


     

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    K-9 Logic

     

    Every month we give away 30 scientist bobble heads to subscribers to The Barker that can answer a riddle or logic problem. If you know the answer to this month’s challenge, click here to submit your answer and have a chance to win a free Gregor Mendel bobble head.

     

    You may recall that in a well-known laboratory there are three post-doctoral researchers, Dr. Green, Dr. Purple and Dr. Orange. Interestingly, and not without its own set of problems, Dr. Green always lies, Dr. Purple alternatively lies and tells the truth, and Dr. Orange always tells the truth.

     

    One day the lab had a visitor who knew the researchers by their first names only (in no particular order – Emma, Ling and Rama) and also a spouse of one of the post docs, Ulli. As the visitor had forgotten the surnames of the three post-docs and to which Ulli was married, she decided to ask each post-doc two questions: i) their last name and ii) to whom was Ulli married.
    Emma responded “I am not Dr. Green, and Ulli is married to Dr. Purple.”
    Ling replied “I am not Dr. Purple and Ulli is married to Dr. Orange.”
    And Rama retorted “I am not Dr. Orange and Ulli is married to Dr. Green.”
    So to whom is Ulli married?