Normal iPSCs

Versatile iPSCs you can depend on
These normal Induced Pluripotent Stem Cells (iPSCs) have been programmed to exhibit maximum pluripotency and stability for your downstream differentiations.

Using a proprietary method that leverages episomal DNA and small molecule inhibitors, these robust iPSC colonies exhibit no karyotypic abnormalities following initial reprogramming.  Cells were programmed using a single transfection step in the absence of proto-oncogenes c-Myc and Lin28 to minimize downstream safety risks for researchers and therapeutic developers.

We offer four different types of normal iPSCs.   All iPSCs are free of Mycoplasma and exhibit classical morphology and growth characteristics. They are also validated for pluripotency based on colony morphology, alkaline phosphatase staining, and expression of SSEA-4.

Click here to see diseased model iPSCs.

Human Foreskin Fibroblast Induced Pluripotent Stem Cells — Cells were isolated from an adult human dermal cell sample and programmed using our patented virus-free method using episomal DNA and our proprietary mix of vectors, excluding l-Myc, c-Myc, and Lin28 transcription factors. Fibroblast cells can be differentiated into neural and epithelial progenitor cells for further use in cell therapy, regenerative medicine, wound healing, and tissue engineering research applications.

Human Multipotent Induced Pluripotent Stem Cells — Cells isolated from cord blood containing lower MHC Class II molecules are programmed using a patented virus-free method using episomal DNA and our proprietary mix of vectors, excluding l-Myc, c-Myc, and Lin28 transcription factors. Multipotent stem cells can self-renew through dividing and can be developed into multiple specific cell types for a particular tissue tropism. These cells can be differentiated into all cell types within one lineage for cell therapy, regenerative medicine, and fertility applications.

Human CD34+ Induced Pluripotent Stem Cells — CD34+ cells isolated from cord blood were reprogrammed with our patented episomal, virus-free method using a proprietary mix of vectors, excluding l-Myc, c-Myc, and Lin28 transcription factors. CD34+ cells contain hematopoietic stem and progenitor cells and are more naive than similar cells derived from other tissue sources. They are reported to have higher proliferative, engraftment, and multipotent potential. These cells can be used in immunology, stem cell biology, and cell therapy research applications.

Human Amniotic Membrane Induced Pluripotent Stem Cells — Cells isolated from amniotic membrane mesenchymal stromal cells and reprogrammed to maximum pluripotency using our patented, non-integrating episomal DNA-based method, which leverages a proprietary mix of transcription factors and a small molecule cocktail to maximize programming efficiency and pluripotency.